Diabetes Disposables : Focus Insulin Delivery Systems
today recognised as a major lifestyle disease in the
India, with the country having possibly the largest number
of diabetics in the world. It’s ageing population;
sedentary lifestyles, high stress levels, improper sleep
and deteriorating eating habits are factors contributing
to India being dubiously hailed as the world’s diabetic
to the International Diabetes Federation report of 2006,
there are around 41 million diabetics in India, which is
expected to rise to 70 million by the year 2025. Having
reached such epidemic levels, there apparently is a need
for novel agents to surface in the market, in particular
the insulin market, which still offers the most widespread
and effective blood sugar lowering treatment.
to the Global Insulin Market report, the global insulin
market currently estimated at $ 7.5 billion, growing at a
compound annual growth rate (CAGR) of 14 per cent is
expected to rise to a whopping $ 14.5 billion by 2010.
This is directly linked to the growing number of
diabetics. This report predicts that approximately 380
million people will suffer from diabetes by 2025. Nearly
one-third of total diabetes patients will be from India
and China. Presently both have fledgling, but emerging
insulin markets. In addition, this report estimates that
60 per cent of the insulin available in the market today
is available in injectable form through syringes, pens,
of these are increasing due to the long duration of
treatment, larger volumes and precise dose. Diabetes and
therefore insulin remains the most important area in the
application of self injecting devices.
insulin delivery methods includes syringes, pens, pumps,
needle-free injectors and inhalers.
developments in the administration of insulin include
inhalable insulin, topical patches, buccal spray insulin,
and nasal/intranasal spray formulations.
syringes and pumps dominate the US market.
users in Europe and Japan continue to use pen devices.
injectors have been launched in the market decades ago,
but so far, have failed to create a major impact.
systems for self administration in particular pens are
well established, and with the increase in their usage,
demand for these devices is progressely increasing.
Delivery devices which look like a large Pen use a
Cartridge rather than a vial for the purpose. Injection
pens are typically multi-dose injectors mainly used for
frequent injections. The dose can be fixed or is variable
depending upon the condition of the sufferer and the
nature of treatment. Injection pens are used with
dedicated drug cartridges and its process (needle
insertion and injection) is usually performed manually.
delivery devices use disposable needles and are used for
the drugs, which require frequent drug administration for
titration of dosage. Injection systems for self
administration are recommended to patients using
particular drug on frequent basis and when the duration of
therapy is long.
Delivery devices are re-usable as well as for a single
use. They come with a refilled cartridge and are disposed
of after the use.