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A TECHNO-ECONOMIC NEWS MAGAZINE FOR MEDICAL PLASTICS AND PHARMACEUTICAL INDUSTRY

Our 28th Year of Publication
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Innovation & Technology

Technologies From IIT Guwahati For COVID 19 Management

A. Overview :

1. Spray / Hand sanitizer:

It has been felt the need for the sanitizers has increased dramatically due the COVID 19 pandemic, which resulted in empty shelves in pharmacies and hospitals. Thus, we have developed a gel-based hand rub sanitizer as per the WHO recommendations and Government regulations. We have formulated a specific chemistry required to prepare sanitizer for different applications. In the same line we have also developed a spray-based solution, which can be sprayed over to any surface to any surface in order to disinfect it. This is necessary for faster cleaning and sanitization in hospitals or isolation wards.

2. Re-Usable filter-based masks and PPE:

The entire world is currently facing the issue of scarcity of masks may it be, normal surgical masks or N95 grade respirator mask. At present, disposable basic surgical mask represents the most popular product type. The demand for these masks can be primarily attributed because of the low cost whereas the cost of Reusable mask is very high. The surgical masks can be used only once, they are non-effective for filtering minute airborne particulate matters. One of the reasons being, such masks although having made out of 3-4 layered polypropylene fabric, they fit loosely on face. Hence making it easier for bacteria and viruses to enter our system. It can only prevent the wearer from spreading the disease, but again these are of one-time use, they should be replaced every time and as they fit loosely on one’s face, they are quite in efficient stop contamination. Further, the migration of water droplets from COVID - 19 infected persons to non-infected people is growing concern.

In view of this background, we have made CAD design for reusable mask and are going to print first few prototypes in coming days. We are also working on improving on design and material so that it can fit well and protect health workers from virus and bacterial attacks. We are also working on preparing a stretchable and reusable superhydrophobic face mask, where extremely water repellent superhydrophobicity would prevent penetration of corona-virus contaminated aqueous droplets through the coated mask and the stretchability would help in getting better fitted mask.

3. Portable UV light-based satirizer:

Our experience in making portable UV-Vis light-based devices for diagnostic application, enabled us to develop the portable UV light-based sterilizer/ disinfectant device. We have also identified various components required and have ideated the initial design. We are going to use UV-C, the shorter and most energetic wavelength of light, which is blocked by the ozone layer, to effectively disinfectant empty rooms, by destroying the genetic material in viral particles. Though there are many side effects on direct exposure, but enclosed in such a way that it can be used to sanitize isolated places or can be made portable for specific sterilization application.

4. Portable Temperature Gun/Infrared non-contact Thermometer to measure body temperature:

We have experience in making portable light-based devices in reflectance/transmittance mode for diagnostic application. Infrared thermometer works on similar principle where we have to measure reflected Infrared light emitted from surface. The IR thermometers use a series of lenses and mirrors to focus the emitted infrared energy on a detector. The detector converts the reflected infrared energy in to an electrical signal, which the ADC of microcontroller turns into a digital temperature reading, as output. Emitted infrared energy is the only energy that can give an accurate surface temperature reading. We have started working on design and integration part of device.

5. Online & On-site ICT based training and tutorials for healthcare workers:

Immediately after the COVID-19 out break was announced as a pandemic by WHO on March 11, 2020, we realized that India was going to be affected, sooner or later. We needed to prepare ourselves. Through a meta-analysis of protocols and experience of various hospitals at the fore-front of managing COVID- 19 patients, ICMR and WHO, we have developed over 100 pages of preliminary protocols and policies covering – risk-categorization of patients using digital technology and follow-up, how to set up COVID-19 hospitals, treatment protocols, rational use of PPE, cleaning schedule of clinical workplaces, principles of quarantine, isolation and detection etc. These have been developed for the Indian context, particularly NE of India.

We have put together a web page for detailed demonstration of the services planned: https://www.iitg.ac.in/covid19dmt/

B. Objectives:

• Alcohol-based hand sanitizer is more convenient compared to hand washing with soap and water in most situations in the healthcare setting. It is generally more effective at killing microorganisms and better tolerated than soap and water. It has been recommended by ICMR and WHO to use it more frequently before consuming food or touching any surfaces in the awake of COVID 19 pandemic.

• The spray-based sanitizer finds its application in hospital set up, where quick disinfecting is required. The alcohol-based formulation can be mass produced and provided to the healthcare system.

• As predicted by experts, the number of positive cases in India will rise many folds; increasing the demand of masks for the patients as well as for the health professionals. Our idea has the following applications: - ensures reusability of the same mask, which will be easy to clean.

- well fitted to face, reducing the spread from the wearer.
- reusable filters, which can be customised according to need.
- will provide at least 70% filtering of particulate matter.
- less material required, so that one can make at least 3 filters from a single surgical mask.

• The electromagnetic energy of high frequency UV causes photo-chemical reactions in nucleic acids (DNA & RNA), destroying their ability to reproduce. With a good UV light sanitizing device, one can clean surfaces like desktops and door handles, sinks and toilets, or those items that are always with a person, like phone, watch, glasses etc.

• Infrared Thermometers are used to detect temperature of body in case of fever which is one of the initial symptoms of Coronavirus. However, this is not a 100% accurate way of detecting COVID-19 cases. Coronavirus is highly contagious disease which spreads on contact, this is reason why people are using infrared thermometer which is “No Contact” process compared to mercury based or the digital thermometers. The proposed idea of non-contact-based thermometer find its application where monitoring of patient’s body temperature for communicable diseases like COVID 19.

• If certain projections are correct, despite our best efforts, the total number of affected persons in India is expected to touch a few millions; requiring many-fold increase in number of hospital beds, over 100,000 ventilators (against current 40,000 ventilators) and a sharp increase in number of health professionals. Thus, our survival is critically dependent on us being able to undertake widespread awareness creation, training and capacity-building of health workers at all levels, including the general population quickly using digital means.

This will ensure that

a. Our existing healthcare personnel would remain safe
b. Asymptomatic but infected healthcare personnel (25-50%) will not spread the disease
c. Patients will receive safer care
d. The community monitoring will be stronger

C. Expected Outcomes:

1. Production of

a. Spray hand sanitizers and localized area sanitizers.
b. Reusable and surgical masks and PPE kits.
c. UV-light disinfectors.
d. Handheld temperature sensor.

2. Online COVID 19 and (as well as non-COVID) ICT based training and tutorials for the frontline health workers

a. Schools for Paramedical Training

D. Details of team members:

Mr. Sahil Jagnani, Research Scholar IIT Guwahati, CEO M/S Primary HealthTech Private Limited
Mr. Ankit Chowdhury, Research Scholar IIT Guwahati, CTO M/S Primary HealthTech Private Limited
Dr. Uttam Manna, Associate Professor, IIT Guwahati
Dr. Satadal Saha, Project Director, Dr B C Roy Super-specialityHospital, IIT Kharagpur
Prof. Siddhartha Sankar Ghosh, Professor, IIT Guwahati
Prof. Dipankar Bandyopadhyay, Professor, IIT Guwahati.

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