|
Emerging Trends In Medical Plastics
|
Aayush Agarwal
General Manager, F (R&D)
Roselabs Group, India |
The
Lucrative Challenges of Pre Filled Syringe Technology
PFS is
taking the parenteral drug delivery industry by storm
in India.Today, 85% of healthcare professional prefer
PFS over other parenteral delivery systems. It
constitutes one of the fastest growing markets in the
pharmaceutical sector with estimated revenues of $2.7
bn in 2010 & predicted to reach $5.20 bn by 2021. |
-
The word PFS is commonly known
as Pre Filled Syringe. When we use the word PFS, it
could be either Pre Fillable Syringe (an empty syringe) or
it could be Pre Filled Syringe (a filled syringe). In this
article PFS stands for the later meaning.
-
A PFS can be of basically two
configurations namely Staked Needle (with needle
assembled) and Leur-Lock (without needle). A whole set of
difference come into picture right from the manufacturing
process to the regulatory requirements of these two
different configurations. When talking about the volumes,
it ranges from 0.2 ml to 10 ml usually, however in some
customized requirements the volumes are as high as 20 ml
and 50 ml.
-
Today, PFS is taking the
parenteral drug delivery industry by storm in India. It is
not at all a new invention but has been around for a long
time even during the world war II. However, its in the
last couple of decades that PFS has become a preference in
the injectable market credited to its numerous benefits.
Thus, making it no more a desired product but now a
required product in many situations.
-
It not only comes under the
drug packaging sector but also is a part of the drug
delivery sector since it performs a dual function of
storage as well as delivery of the drug. Today, 85% of
healthcare professional prefer PFS over other parenteral
delivery systems.
PFS Market:
-
PFS constitutes one of the
fastest growing markets in the pharmaceutical sector with
estimated revenues of $2.7 bn in 2010. These are predicted
to reach $3.92 bn by 2015, $4.6 bn by 2018 and $5.20 bn by
2021. Some of the key players in the global market include
Becton & Dickinson (BD), SCHOTT, Abbot Laboratories,
Gerresheimer and others but the key influencer would be
the companies which are setting up in developing nations
like India and China. Such companies include Roselabs
Group of companies in India and Weigao Holding in China.
-
However, US (40% share) is the
largest market and the fastest growing market for PFS
followed by Japan market. This small nation shares over
10% of the world market with China (3.4%) and India (1.2%)
standing at 6th and 9th position respectively. But the
good news is India’s market is one of the fastest growing
markets at close to 8% every year over the next 10 years.
Some of the most commonly
marketed drugs in PFS:
-
Insulin preparations like
Novorapid and Novomix, treatment for rheumatoid arthritis
namely Enbrel and Humira, cotreatment with chemotherapy in
cancer patients namely Neulasta. In India, Enoxaparin is a
popular product in PFS delivery system.
-
Other diseases treatments
where PFS products are seeing a tremendous growth and
opportunity are Osteoporosis, Multiple sclerosis,
Fertility, Anaemia, Haemophilia to name a few. While is
case of therapeutic areas, Vaccines, Anti-coagulants,
Antiinflammatory, Hormones and Pain relievers serve as the
major areas. Specific to Biological drugs, the market is
driven by Monoclonal antibodies, Insulins, Erythropoetins,
Interferons, G-CSF etc.
-
In case of vaccines, Typhoid
live, BCG live, yellow fever, rabies, measles, mumps and
rubella are some of the market driving formulations.
Various benefits associated with PFS:
Page
1 :
2 :
3 |
